Oxidation of an oil rich in docosahexaenoic acid compared to linoleic acid in lactating women.
نویسندگان
چکیده
BACKGROUND We studied the oxidation of an oil rich in docosahexaenoic acid (DHA; DHASCO((R))) in lactating mothers receiving a dietary DHA supplement or a placebo. The results were compared with the oxidation of linoleic acid. METHODS Breast-feeding mothers received a dietary supplement (DHASCO; 200 mg DHA/day, n = 5) or a placebo (n = 5) for 14 days. Six weeks post partum all 10 mothers received a single dose of 2 mg/kg body weight uniformly (13)C-labeled DHASCO. In a previously reported study 6 mothers received 1 mg/kg body weight uniformly (13)C-labeled linoleic acid. Breath samples were collected over 48 h after tracer application. The total CO(2) production was measured by indirect calorimetry and the (13)C isotopic enrichment of labeled CO(2) by isotopic ratio mass spectrometry. RESULTS The oxidation of (13)C-labeled DHASCO in the supplemented and placebo groups was similar. Maximal (13)C enrichment was reached earlier in the group receiving (13)C-DHASCO (median 1.0 vs. 3.0 h in the linoleic acid group). The cumulative (13)C recovery in breath was higher in the DHASCO versus the linoleic acid group until 10 h after tracer application and comparable thereafter. CONCLUSIONS The difference in oxidation of DHASCO versus linoleic acid after tracer ingestion might be partly due to a faster absorption and oxidation of shorter chain saturated fatty acids contained in DHASCO. The cumulative oxidation of DHASCO and linoleic acid 24 and 48 h after tracer ingestion is similar.
منابع مشابه
Squid (Loligo loligo ): The new source to extract omega-3 and omega-6 rich marine oils
Squids belong to the cephalopod family, which composes more than 5% of the total annual fishing volume of southern Iran as by- products; however, these do not have significant usage in Iran. This product was studied to extract the high-value products, i.e. marine oils rich in unsaturated multiple-band fatty acids from 50kg squid (Loligo loligo) obtained from Chabahar fishing port and transferre...
متن کاملSquid (Loligo loligo ): The new source to extract omega-3 and omega-6 rich marine oils
Squids belong to the cephalopod family, which composes more than 5% of the total annual fishing volume of southern Iran as by- products; however, these do not have significant usage in Iran. This product was studied to extract the high-value products, i.e. marine oils rich in unsaturated multiple-band fatty acids from 50kg squid (Loligo loligo) obtained from Chabahar fishing port and transferre...
متن کاملDocosahexaenoic acid level of breast milk of iranian women in low fish – consuming and high fish – consuming regions
Objective: Sufficient intakes of docosahexaenoic acid (DHA) via breast milk are required for optimizing visual and neural development at early stages of life. Little or no information is available on DHA intakes and levels found in breast milk in Iranian women and surrounding regions. In this study we measure the DHA in the breast milk of lactating Iranian women from low and high – fish-eating ...
متن کاملThe Effects of Docosahexaenoic Acid Oil and Soybean Oil on the Expression of Lipid Metabolism Related mRNA in Pigs*
To study the acute effect of dietary docosahexaenoic acid (DHA, C22:6) on the expression of adipocyte determination and differentiation-dependent factor 1 (ADD1) mRNA in pig tissues, weaned, crossbred pigs (28 d of age) were fed with either 10% (on as-fed basis) tallow (high stearic acid), soybean oil (high linoleic acid), or high DHA algal oil for 2 d. The plasma and liver DHA reflected the co...
متن کاملEffects of dietary conjugated linoleic acid and linoleic:linolenic acid ratio on polyunsaturated fatty acid status in laying hens.
A study was conducted to determine the effects of dietary conjugated linoleic acid (CLA) and the ratio of linoleic:linolenic acid on long-chain polyunsaturated fatty acid status. Thirty-two 31-wk-old White Leghorn hens were randomly assigned to four diets containing 8.2% soy oil, 4.1% soy oil + 2.5% CLA (4.1% CLA source), 4.1% flax oil + 2.5% CLA, or 4.1% soy oil + 4.1% flax oil. Hens were fed ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Annals of nutrition & metabolism
دوره 43 6 شماره
صفحات -
تاریخ انتشار 1999